Sight Unseen follows Tess Avery, a top homicide detective who is forced to quit the job she loves after nearly killing her partner and being diagnosed as clinically blind. Reluctant to accept help, Tess uses an assistance app and connects with Sunny Patel, a professional seeing-eye guide and an agoraphobe living 3,000 miles away. After losing her vision, Tess is haunted by the unsolved cases she left behind. Using a hidden camera and earpiece, Sunny remotely steers Tess through life's obstacles – and crimes – as the two challenge preconceptions about ability, trust, and where to draw the line. Inspired by one of the co-creators' experiences with sight loss, viewers join Tess and Sunny as they bring a fresh perspective to solving crime.